{"id":64206,"date":"2023-04-29T11:15:32","date_gmt":"2023-04-29T15:15:32","guid":{"rendered":"https:\/\/cablemanpro.com\/wallstreetpr\/melatonin-gummies-found-to-contain-potentially-dangerous-levels-of-the-hormone-study-64206"},"modified":"2023-04-29T11:15:32","modified_gmt":"2023-04-29T15:15:32","slug":"melatonin-gummies-found-to-contain-potentially-dangerous-levels-of-the-hormone-study","status":"publish","type":"post","link":"https:\/\/cablemanpro.com\/wallstreetpr\/melatonin-gummies-found-to-contain-potentially-dangerous-levels-of-the-hormone-study-64206","title":{"rendered":"Melatonin gummies found to contain potentially dangerous levels of the hormone: study"},"content":{"rendered":"
\n

Melatonin has soared in popularity as a treatment for insomnia<\/u><\/a> and jet lag, with adults five times likelier to use it in 2018 compared to 2000, per the nonprofit National Sleep Foundation, based in Washington, D.C.\u00a0<\/p>\n

More than 60% of surveyed adults who take melatonin use the gummy form \u2014 but a recent study in the Journal of the American Medical Association (JAMA) suggested that the contents of those gummies might not exactly match what\u2019s noted on the bottle.<\/p>\n

Researchers from the Cambridge Health Alliance in Somerville, Massachusetts<\/u><\/a> and the University of Mississippi evaluated 25 unique brands of gummies that were purchased online and included “melatonin” as an ingredient on their labels.\u00a0<\/p>\n

IN ALZHEIMER\u2019S STUDY, SLEEPING PILLS ARE SHOWN TO REDUCE SIGNS OF DISEASE IN THE BRAIN<\/u><\/strong><\/a><\/p>\n

Twenty-two of the 25 gummy brands test (88%) were inaccurately labeled, the study found.<\/p>\n

Only three of the products contained within 10% of the amount of melatonin that was indicated on the label, with the actual amounts of the hormone ranging from 74% to 347%. One contained CBD (cannabidiol) \u2014 but no melatonin at all.<\/p>\n

Of the five products that declared CBD as an ingredient, the actual amount was more than 100% in excess of the amount listed on the label.<\/p>\n

“Non-prescription forms of CBD can contain trace amounts of THC (less than 3% by weight),” Dr. Kelly Johnson-Arbor, <\/strong>a medical toxicologist at the National Capital Poison Center in Washington, D.C.<\/a>, told Fox News Digital.\u00a0<\/p>\n

“When people consume large amounts of CBD, they may also ingest significant amounts of THC that can potentially cause positive results on drug tests, unexpected signs or symptoms or even toxicity.”<\/p>\n

Johnson-Arbor was not involved in the new study.<\/p>\n

MELATONIN SHOULD BE AVOIDED IN CHILDREN UNLESS DIRECTED BY A HEALTH CARE PROFESSIONAL, SAYS SLEEP ACADEMY<\/strong><\/a><\/p>\n

All of the gummies tested were included in the National Institutes of Health\u2019s Dietary Supplement Label Database, which is considered the most comprehensive database of dietary supplements available in the U.S.<\/p>\n

“We know from prior studies that manufacturing standards can be poor when it comes to supplements, but I was particularly surprised that there was too much melatonin in many of the products,” lead study author Dr. Pieter Cohen, associate professor of medicine at the Cambridge Health Alliance at Harvard Medical School in Somerville, Massachusetts, told Fox News Digital via email\u00a0this week. <\/p>\n

“I was also surprised that CBD was found in the products listed in the NIH’s dietary supplement website, as the FDA has been clear that CBD is not a legal supplement ingredient,” he added.<\/p>\n

“While melatonin is not highly toxic in pure form, the presence of contaminants greatly increases the risk of unexpected toxic effects from use of the product,” said Johnson-Arbor.<\/p>\n

The gummy version of melatonin supplements may appeal to kids, but Cohen said it\u2019s important to remember that it\u2019s a medication<\/u><\/a> \u2014 “just like Benadryl or Tylenol.”<\/p>\n

“With that in mind, we should keep it secure from children and not give extra if the first dose is not working,” he said.\u00a0<\/p>\n

“If consumers decide to try melatonin \u2014 particularly if giving it to children \u2014 they should seek out a product that is certified by either USP (United States Pharmacopeia) or NSF (formerly the National Sanitation Foundation, now NSF International), as that is the only way to be certain that the product is accurately labeled.”<\/p>\n

WANT TO GET BETTER SLEEP? EXERCISE FOR THIS LONG EACH DAY<\/u><\/strong><\/a><\/p>\n

Adults are giving an increasing amount of melatonin to children. Between 2012 and 2021, the number of “pediatric ingestions” of melatonin each year rose 530%, according to the Centers for Disease Control and Prevention (CDC).<\/p>\n

Too much melatonin can be dangerous for children<\/u><\/a> \u2014 and reports of overdoses are on the rise.<\/p>\n

Medical emergencies and hospitalizations have increased, the CDC stated, largely due to a rise in “unintentional melatonin ingestions” by children aged 5 years and younger.<\/p>\n

“If young children take too much melatonin, it can lead to serious consequences, as we saw in a U.S. Poison Control study from last year,” Cohen told Fox News Digital.\u00a0<\/p>\n

“That study showed that 27,795 kids required medical evaluation, 4,097 were hospitalized and two died after taking too much melatonin.”<\/p>\n

Because it is considered a dietary supplement in the U.S., melatonin is not approved by or regulated by the U.S. Food and Drug Administration (FDA) for safety or effectiveness, the FDA said in a statement to Fox News Digital. (In several other countries, melatonin is considered a drug and is only available by prescription.)\u00a0<\/p>\n

“The FDA collects and tests dietary supplements as part of the agency\u2019s routine monitoring of the marketplace and investigations of suspected problems; however, the FDA does not test dietary supplements before they are sold to consumers due to limited resources,” the agency said in its statement.<\/p>\n

“Firms have the primary responsibility to make sure their products are not adulterated or misbranded before they are distributed,” the FDA continued.\u00a0<\/p>\n

“The dietary supplement good manufacturing practices requires that firms establish both specifications for ingredients in dietary supplements as well as specifications for finished products and to verify that those specifications are met.”<\/p>\n

Although there is not an “official” recommended dosage, the Mayo Clinic has stated the “typically recommended maximum dose” as 5 or fewer milligrams for adults.<\/p>\n

When it comes to children, there are some conflicting recommendations in the absence of an FDA recommendation.<\/p>\n

“We use a maximum dose of 3 mg for children less than 88 lbs and 5 mg for children more than 88 lbs,” Dr. Craig Canapari, a pediatric sleep physician at Yale-New Haven Children\u2019s Hospital in New Haven, Connecticut<\/u><\/a>, wrote on his website.<\/p>\n

SOME 20% OF AMERICANS ARE TAKING SLEEP MEDICATIONS, CDC SAYS: ‘ALARMING’ DATA<\/u><\/strong><\/a><\/p>\n

“With more than 1% of U.S. children using melatonin supplements, I expect these results to be of immediate importance to parents of all children using \u2014 or considering using \u2014 melatonin,” said study author Cohen.<\/p>\n

He emphasized the need for accurately labeled supplements on store shelves.\u00a0<\/p>\n

“We will need to ask Congress to make some changes to the law to ensure that American consumers can have ready access to high-quality supplements,” Cohen added.<\/p>\n

This is the first U.S. study to evaluate the quantity of melatonin in over-the-counter melatonin products, the researchers wrote in a discussion of the findings.<\/p>\n

But Cohen said they cannot predict the outcome from bottle to bottle.<\/p>\n

“We also only looked at gummies \u2014 we don’t yet know if other forms of melatonin (tablets or capsules) have the same problems,” he added.<\/p>\n

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER<\/u><\/strong><\/a><\/p>\n

“Even if a melatonin product is labeled as \u2018organic\u2019 or \u2018safe,\u2019 it may still contain undeclared contaminants or higher concentrations of ingredients than listed on the package label,\u00a0due to lack of stringent federal oversight,” warned Johnson-Arbor.\u00a0<\/p>\n

“Consumers must be aware of the potential for dietary supplements to contain contaminants or have variable potency, and should use all dietary supplements with care,” she added.<\/p>\n

“Because children may be more susceptible than adults to the effects of undeclared contaminants, parents and caregivers<\/a> should speak with a\u00a0pediatrician before giving their children dietary supplements \u2014 including melatonin.”<\/p>\n<\/div>\n

Source – https:\/\/www.foxnews.com\/health\/melatonin-gummies-found-contain-potentially-dangerous-levels-hormone-study <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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