{"id":139618,"date":"2026-07-19T12:04:36","date_gmt":"2026-07-19T16:04:36","guid":{"rendered":"https:\/\/cablemanpro.com\/wallstreetpr\/millions-warned-that-popular-summer-fruit-can-seriously-interfere-with-medications-139618"},"modified":"2026-07-19T12:04:36","modified_gmt":"2026-07-19T16:04:36","slug":"millions-warned-that-popular-summer-fruit-can-seriously-interfere-with-medications","status":"publish","type":"post","link":"https:\/\/cablemanpro.com\/wallstreetpr\/millions-warned-that-popular-summer-fruit-can-seriously-interfere-with-medications-139618","title":{"rendered":"Millions warned that popular summer fruit can seriously interfere with medications"},"content":{"rendered":"
\n

Amid this summer’s sweltering temperatures, many people are finding relief by sipping fruity cocktails and smoothies<\/a> or drinking fruit juices.<\/p>\n

But a doctor is warning millions of people taking common medications<\/a> such as statins and antidepressants that ingesting grapefruit \u2014 a common “healthy” ingredient in many summer snacks and drinks \u2014 can have serious consequences.<\/p>\n

“Grapefruit is a pleasant snack for most, but it is important to disclose large amounts of grapefruit use to your doctor because it can interact with an array of medications,” Dr. Nicole James, a doctor based in Illinois, told news agency SWNS.<\/p>\n

GRAPEFRUIT COULD MAKE YOUR COFFEE BUZZ LAST LONGER AS EXPERTS WARN OF HIDDEN RISKS<\/strong><\/a><\/p>\n

Common cocktails that contain grapefruit include palomas, greyhounds, some margaritas and sea breezes.<\/p>\n

“Grapefruit contains<\/a> natural compounds \u2014 primarily furanocoumarins and flavonoids. These inhibit an important enzyme called cytochrome P450 3A4,” James said.\u00a0<\/p>\n

This enzyme is referred to as CYP3A4.<\/p>\n

\u00a0It plays an important role in breaking down oral medications so that the body can properly process them.<\/p>\n

“When you ingest grapefruit, it blocks this enzyme,” said James, who is also a clinical research fellow<\/a> in the department of dermatology at Stanford University.<\/p>\n

CELEBRITY CHEF SAYS IF YOU CAN DRIVE TO MCDONALD’S, YOU CAN COOK HEALTHY MEALS AT HOME<\/strong><\/a><\/p>\n

“This causes drugs that would normally be broken down in the gut wall to instead pass through intact, leading to significantly higher-than-intended blood levels of the medication,” James added.\u00a0<\/p>\n

Having higher concentrations of a medication than normal can cause serious side effects.<\/p>\n

Drug concentrations in the blood can rise too fast and to dangerously high levels, Harvard Medical School also noted, as Fox News Digital previously reported.\u00a0<\/p>\n

CLICK HERE FOR MORE LIFESTYLE STORIES<\/u><\/strong><\/a><\/p>\n

“Patients taking statins could experience higher levels than normal, which can cause muscle breakdown and cramps,” James noted.<\/p>\n

Meanwhile, patients taking certain blood pressure medications<\/a> like amlodipine “may experience dizziness and low blood pressure.”<\/p>\n

Sedatives can also pose a risk, with medications like midazolam being impacted by grapefruit and causing “extreme drowsiness and even slowed breathing,” she said.\u00a0<\/p>\n

Antidepressants like sertraline also come with a warning to avoid the fruit.<\/p>\n

CLICK HERE TO SIGN UP FOR OUR LIFESTYLE NEWSLETTER<\/u><\/strong><\/a><\/p>\n

For those who think it would take a lot grapefruit to have an effect \u2014 James said this isn\u2019t the case.<\/p>\n

“As little as one grapefruit or 200 mL of juice can cause a clinically relevant increase in medication concentrations, and the effect can last up to 72 hours because grapefruit irreversibly inactivates CYP3A4 enzyme,” she said.<\/p>\n

People should keep an eye on mixed fruit juices<\/a>, smoothies and cocktails, as grapefruit juice is a common ingredient, she said.<\/p>\n

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ<\/u><\/strong><\/a><\/p>\n

“If patients ingest a large amount of grapefruit while on these medications, they should monitor for any symptoms<\/a> and avoid ingesting any more grapefruit,” said James, advising people to always seek medical attention if there are any concerns.<\/p>\n

The doctor also warned about other ingredients that patients should be aware of \u2014 and reiterated that reaching out to healthcare professionals ahead of time is always a wise move.\u00a0<\/p>\n

Among the ingredients to watch:<\/p>\n<\/div>\n

Source – https:\/\/www.foxnews.com\/food-drink\/millions-warned-popular-summer-fruit-can-seriously-interfere-medications <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Amid this summer’s sweltering temperatures, many people are finding relief by sipping fruity cocktails and smoothies or drinking fruit juices. 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