{"id":137909,"date":"2026-07-04T11:55:29","date_gmt":"2026-07-04T15:55:29","guid":{"rendered":"https:\/\/cablemanpro.com\/wallstreetpr\/why-scratching-a-mosquito-bite-makes-it-so-much-worse-according-to-science-137909"},"modified":"2026-07-04T11:55:29","modified_gmt":"2026-07-04T15:55:29","slug":"why-scratching-a-mosquito-bite-makes-it-so-much-worse-according-to-science","status":"publish","type":"post","link":"https:\/\/cablemanpro.com\/wallstreetpr\/why-scratching-a-mosquito-bite-makes-it-so-much-worse-according-to-science-137909","title":{"rendered":"Why scratching a mosquito bite makes it so much worse, according to science"},"content":{"rendered":"<div>\n<p>Scratching a bug bite or rash may seem irresistible, but it\u2019ll only provide <a href=\"https:\/\/www.foxnews.com\/health\" target=\"_blank\" rel=\"noopener noreferrer\">temporary relief<\/a> and likely prolong the itch, researchers found.<\/p>\n<p>Scratching is a natural response to a skin irritant that increases skin inflammation and can make certain diseases, <a href=\"https:\/\/foxnews.com\/category\/health\/beauty-and-skin\/eczema\" target=\"_blank\" rel=\"noopener noreferrer\">such as eczema<\/a>, worse. But why scratching exacerbates swelling and whether the evolutionary response offers any benefit is something University of Pittsburgh researchers said remained &#8220;poorly explored.&#8221;<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/newsletters?cmpid=fnfirstnl\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>CLICK HERE TO SIGN UP FOR OUR LIFESTYLE NEWSLETTER<\/strong><\/a><\/p>\n<p>To investigate the relationship between itch, scratching and inflammation, the researchers, led by University of Pittsburgh professor of dermatology and immunology Daniel H. Kaplan, <a href=\"https:\/\/foxnews.com\/category\/health\/respiratory-health\/allergy\" target=\"_blank\" rel=\"noopener noreferrer\">applied an allergen<\/a> to the ears of mice to trigger allergic-contact dermatitis, an eczema-like inflammatory skin condition.<\/p>\n<p>The mice developed the type of skin reaction people commonly have to poison ivy, certain metals, like nickel, and some skincare ingredients.<\/p>\n<p>One group of mice was designated as &#8220;normal,&#8221; while another group was genetically modified to lack an itch-sensing neuron.<\/p>\n<p>A set of mice was allowed to scratch freely, while another was prevented from scratching with an Elizabethan-style collar, often referred to as the &#8220;cone of shame&#8221; among pet owners.<\/p>\n<p>The researchers found that scratching activated mast cells, which the <a href=\"https:\/\/my.clevelandclinic.org\/health\/body\/mast-cells\" target=\"_blank\" rel=\"noopener noreferrer\">Cleveland Clinic describes<\/a> as part of the body&#8217;s &#8220;alarm system&#8221; that &#8220;look out for harmful invaders.&#8221; Mast cells release histamine and other inflammatory chemicals that cause itchiness.<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/category\/lifestyle\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>CLICK HERE FOR MORE LIFESTYLE NEWS<\/strong><\/a><\/p>\n<p>&#8220;Sometimes, they activate when they shouldn\u2019t, causing allergic reactions,&#8221; Cleveland Clinic explained.<\/p>\n<p>The researchers found the mice that scratched freely released more substance P, a signaling molecule that activated more mast cells, causing increased inflammation and a prolonged itch-scratch cycle.<\/p>\n<p>The mice that were prevented from scratching and those lacking the itch-sensing neuron experienced less inflammation.<\/p>\n<p>Scratching is satisfying, however, and <a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adv1573\" target=\"_blank\" rel=\"noopener noreferrer\">Science reported<\/a> &#8220;The capacity to both sense itch and behaviorally respond by scratching evolved hundreds of millions of years ago.&#8221;<\/p>\n<p>Because mast cells are &#8220;also important for protecting against bacteria and other pathogens,&#8221; the researchers performed another experiment to determine &#8220;if scratching-induced activation of mast cells could affect the skin microbiome,&#8221; University of Pittsburgh reported in a <a href=\"https:\/\/www.medschool.pitt.edu\/news\/why-you-shouldn-t-scratch-itchy-rash-new-study-explains\" target=\"_blank\" rel=\"noopener noreferrer\">news release.<\/a><\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/category\/lifestyle\/quizzes\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ<\/strong><\/a><\/p>\n<p>The scientists found that scratching reduced levels of Staphylococcus aureus, one of the bacteria most associated with skin infections.<\/p>\n<p>&#8220;The damage that scratching does to the skin probably outweighs this benefit when itching is chronic,&#8221; Kaplan cautioned.<\/p>\n<p>&#8220;At first, these findings seemed to introduce a paradox: if scratching an itch is bad for us, why does it feel so good?&#8221; he said. &#8220;Scratching is often pleasurable, which suggests that, in order to have evolved, this behavior must provide some kind of benefit. Our study helps resolve this paradox by providing evidence that scratching also provides defense against bacterial skin infections.&#8221;<\/p>\n<p>According to the American Academy of Dermatology, cold compresses and <a href=\"https:\/\/foxnews.com\/category\/health\/healthy-living\/medications\" target=\"_blank\" rel=\"noopener noreferrer\">1% hydrocortisone cream<\/a> may help relieve itching.<\/p>\n<p>The researchers published their findings in the <a href=\"https:\/\/www.science.org\/doi\/10.1126\/science.adn9390\" target=\"_blank\" rel=\"noopener noreferrer\">journal Science<\/a> last year.<\/p>\n<\/div>\n<p><a href=\"https:\/\/www.foxnews.com\/lifestyle\/why-scratching-mosquito-bite-makes-so-much-worse-according-science\">Source &#8211; https:\/\/www.foxnews.com\/lifestyle\/why-scratching-mosquito-bite-makes-so-much-worse-according-science <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scratching a bug bite or rash may seem irresistible, but it\u2019ll only provide temporary relief and likely prolong the itch, researchers found. Scratching is a [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":{"twitter_2902945987_2902945987":""},"rop_publish_now_history":[],"rop_publish_now_status":"pending","footnotes":""},"categories":[16563],"tags":[],"stock_ticker":[],"class_list":["post-137909","post","type-post","status-publish","format-standard","hentry","category-market-news","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Why scratching a mosquito bite makes it so much worse, according to science - Wall Street PR<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cablemanpro.com\/wallstreetpr\/why-scratching-a-mosquito-bite-makes-it-so-much-worse-according-to-science-137909\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Why scratching a mosquito bite makes it so much worse, according to science - Wall Street PR\" \/>\n<meta property=\"og:description\" content=\"Scratching a bug bite or rash may seem irresistible, but it\u2019ll only provide temporary relief and likely prolong the itch, researchers found. 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