{"id":130001,"date":"2026-04-30T07:00:19","date_gmt":"2026-04-30T11:00:19","guid":{"rendered":"https:\/\/cablemanpro.com\/wallstreetpr\/early-parkinsons-warning-signs-may-be-hiding-in-the-gut-study-finds-130001"},"modified":"2026-04-30T07:00:19","modified_gmt":"2026-04-30T11:00:19","slug":"early-parkinsons-warning-signs-may-be-hiding-in-the-gut-study-finds","status":"publish","type":"post","link":"https:\/\/cablemanpro.com\/wallstreetpr\/early-parkinsons-warning-signs-may-be-hiding-in-the-gut-study-finds-130001","title":{"rendered":"Early Parkinson\u2019s warning signs may be hiding in the gut, study finds"},"content":{"rendered":"
\n

Specific bacteria<\/a> in the gut could predict a person\u2019s risk of developing Parkinson\u2019s disease years before symptoms appear, new research suggests.<\/p>\n

Led by researchers from University College London (UCL), an observational study analyzed the gut microbes of 271 patients in the U.K. who had been diagnosed with Parkinson\u2019s.<\/p>\n

Also included in the study were 43 carriers of the GBA1 variant, which has been linked to an almost 30 times higher risk of Parkinson\u2019s disease<\/a>. These participants did not have symptoms of the disease. There was also a control group of 150 healthy participants without the gene.<\/p>\n

STUDY FINDS EVIDENCE OF MICROPLASTICS IN BRAINS AND OTHER ORGANS<\/strong><\/a><\/p>\n

Based on fecal samples, more than one-quarter of gut microbes \u2014 bacteria and other microorganisms in the digestive tract \u2014 were in different amounts for people with Parkinson\u2019s disease compared to healthy individuals, according to a press release.<\/p>\n

Non-symptomatic people carrying the Parkinson\u2019s gene also had microbial changes that resembled an “intermediate” stage of the disease, which suggests that microbial changes may happen prior to symptoms emerging.<\/p>\n

Those who reported eating a more diverse and balanced diet<\/a> were less likely to have microbiome patterns associated with higher Parkinson\u2019s risk, the researchers found.<\/p>\n

The findings, which were published in Nature Medicine, were also seen in over 1,400 participants across the U.K., Korea and Turkey, suggesting that the microbial changes are consistent across different cultures and dietary patterns.<\/p>\n

“Parkinson\u2019s disease is a major cause of disability worldwide, and the fastest growing neurodegenerative disease<\/a> in terms of prevalence and mortality,” lead author Professor Anthony Schapira of the UCL Queen Square Institute of Neurology said in the release.\u00a0\u00a0<\/p>\n

“There is an urgent need to develop treatments that can stop or slow the disease\u2019s progression.”<\/p>\n

ALZHEIMER’S RISK COULD RISE WITH COMMON CONDITION AFFECTING MILLIONS, STUDY FINDS<\/strong><\/a><\/p>\n

Patients with Parkinson’s are known to have “significant gut abnormalities,” according to Dr. Earnest Lee Murray, a board-certified neurologist at Jackson-Madison County General Hospital in Jackson, Tennessee.<\/p>\n

One of those is severe constipation, which can occur several years before tremors and other symptoms.\u00a0<\/p>\n

“There has long been a theory about the gut-brain axis<\/a> and whether or not the pathology for Parkinson’s starts in the gut decades before stereotypical features are noted,” Murray, who was not involved in the research, told Fox News Digital.<\/p>\n

The neurologist said the study sets the stage for additional research exploring the gut-brain axis theory, which could determine whether early pre-symptomatic treatments could prevent or mitigate the risk of developing Parkinson’s later in life.<\/p>\n

\u00a0CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER<\/strong><\/a><\/p>\n

“With an aging population that is living longer, the prevalence of Parkinson’s<\/a> is increasing significantly, which underscores the importance of studies like this that attempt to prevent this debilitating neurodegenerative disease,” Murray added.<\/p>\n

Dr. Aaron Ellenbogen, medical director of the Parkinson\u2019s Disease & Movement Disorders Center at the Michigan Institute for Neurological Disorders, said it is not surprising that a change in the organisms living in the GI tract <\/a>can be a signature of evolving Parkinson’s pathology.<\/p>\n

“In general, people with GBA mutations tend to have Parkinson’s symptoms evolve in a way that is more consistent with a gut-first presentation,” Ellenbogen, who also was not involved in the study, told Fox News Digital.\u00a0\u00a0<\/p>\n

Others may experience a different set of symptoms, including loss of sense of smell, before developing signs of motor Parkinson’s disease, he noted.<\/p>\n

CLICK HERE FOR MORE HEALTH STORIES<\/strong><\/a><\/p>\n

“In fact, many of these people don’t develop the symptoms of constipation and REM behavior disorder until later in their disease course,” Ellenbogen said. “These people may actually have a form of Parkinson’s that starts in the brain.”<\/p>\n

There were some limitations to the study, the researchers acknowledged. Because it was observational in design, it could not prove that the microbiome changes directly caused Parkinson\u2019s.<\/p>\n

The researchers also noted that not everyone with at-risk microbiome profiles will develop the disease, as other genetic or environmental factors<\/a> could play a role.<\/p>\n

Additionally, differences in microbiomes across various populations could skew the results.<\/p>\n

“To enable both the research and eventual use of such treatments<\/a>, we need to develop the means for very early detection of people who will, or likely will, go on to develop the disease,” Schapira said.<\/p>\n

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ<\/strong><\/a><\/p>\n

The study was funded by the Michael J. Fox Foundation for Parkinson\u2019s Research and the UK Medical Research Council.<\/p>\n

Fox News Digital reached out to the researchers for comment.<\/p>\n<\/div>\n

Source – https:\/\/www.foxnews.com\/health\/early-parkinsons-warning-signs-may-hiding-gut-study-finds <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Specific bacteria in the gut could predict a person\u2019s risk of developing Parkinson\u2019s disease years before symptoms appear, new research suggests. 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