{"id":128695,"date":"2026-04-21T20:22:33","date_gmt":"2026-04-22T00:22:33","guid":{"rendered":"https:\/\/cablemanpro.com\/wallstreetpr\/common-eating-habit-may-trigger-premature-immune-system-aging-study-finds-128695"},"modified":"2026-04-21T20:22:33","modified_gmt":"2026-04-22T00:22:33","slug":"common-eating-habit-may-trigger-premature-immune-system-aging-study-finds","status":"publish","type":"post","link":"https:\/\/cablemanpro.com\/wallstreetpr\/common-eating-habit-may-trigger-premature-immune-system-aging-study-finds-128695","title":{"rendered":"Common eating habit may trigger premature immune system aging, study finds"},"content":{"rendered":"
\n

Eating too much salt has long been linked to high blood pressure<\/a>, but new research suggests that it could trick the immune system into prematurely aging the blood vessels.<\/p>\n

A preclinical study recently published in the Journal of the American Heart Association has identified a biological chain reaction that links a salty diet<\/a> to cardiovascular decay.<\/p>\n

Scientists at the University of South Alabama observed that mice on a high-salt diet experienced rapid deterioration in their blood vessel function.<\/p>\n

HIGH SALT INTAKE LINKED TO FASTER MEMORY DECLINE IN ONE GROUP, STUDY FINDS<\/strong><\/a><\/p>\n

After just four weeks of high sodium intake<\/a>, the small arteries responsible for regulating blood flow lost their ability to relax, as shared in a press release.<\/p>\n

The team found that the cells lining these vessels had entered a state of cellular senescence \u2014 a form of premature cellular aging in which cells stop dividing and release a mix of inflammatory signals that can damage surrounding tissue.<\/p>\n

The researchers tried to replicate this damage by exposing blood vessel cells directly to salt in a laboratory dish, but the cells showed no harmful effects.<\/p>\n

CLICK HERE FOR MORE HEALTH STORIES<\/u><\/strong><\/a><\/p>\n

This suggests that salt isn\u2019t directly causing damage to the vascular lining, but that the real culprit may be the body\u2019s own defense mechanism, the researchers noted.<\/p>\n

Excess salt may trigger the immune system<\/a> to release a molecule called interleukin-16 (IL-16), which acts as a messenger that instructs blood vessel cells to grow old before their time, according to the study.<\/p>\n

Once these cells age, they fail to produce nitric oxide, the essential gas that tells arteries to dilate and stay flexible.<\/p>\n

To test whether this process could be reversed, the team turned to a class of experimental drugs<\/a> known as senolytics.<\/p>\n

Using a cancer medication<\/a> called navitoclax, which selectively clears out aged and dysfunctional cells, the researchers were able to restore nearly normal blood vessel function in the salt-fed mice, the release stated.<\/p>\n

TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ<\/u><\/strong><\/a>.<\/p>\n

By removing the decaying cells created by the high-salt diet, the drug allowed the remaining healthy tissue to maintain its elasticity and respond correctly to blood flow demands.<\/p>\n

The study did have some limitations. The transition from mouse models to human treatment<\/a> remains a significant hurdle, the team cautioned.<\/p>\n

CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER<\/u><\/strong><\/a><\/p>\n

Senolytic drugs like navitoclax are still being studied for safety, and the team emphasized that previous trials have shown mixed results regarding their impact on artery plaque.<\/p>\n

Additionally, the researchers have not yet confirmed whether the same IL-16 pathway is the primary driver of vascular aging in humans.<\/p>\n<\/div>\n

Source – https:\/\/www.foxnews.com\/health\/common-eating-habit-may-trigger-premature-immune-system-aging-study-finds <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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