{"id":123799,"date":"2026-03-10T14:19:22","date_gmt":"2026-03-10T18:19:22","guid":{"rendered":"https:\/\/cablemanpro.com\/wallstreetpr\/lurking-dementia-risk-exposed-by-breakthrough-test-25-years-before-symptoms-123799"},"modified":"2026-03-10T14:19:22","modified_gmt":"2026-03-10T18:19:22","slug":"lurking-dementia-risk-exposed-by-breakthrough-test-25-years-before-symptoms","status":"publish","type":"post","link":"https:\/\/cablemanpro.com\/wallstreetpr\/lurking-dementia-risk-exposed-by-breakthrough-test-25-years-before-symptoms-123799","title":{"rendered":"Lurking dementia risk exposed by breakthrough test 25 years before symptoms"},"content":{"rendered":"<div>\n<p>A new blood test could determine a <a href=\"https:\/\/www.foxnews.com\/category\/health\/healthy-living\/womens-health\" target=\"_blank\" rel=\"noopener\">woman\u2019s dementia risk<\/a> as early as 25 years before symptoms emerge.<\/p>\n<p>That\u2019s according to new research from the University of California San Diego, which found that a specific biomarker protein associated with early pathological processes of Alzheimer\u2019s disease was &#8220;strongly linked&#8221; to future dementia risk.<\/p>\n<p>The researchers analyzed blood samples from 2,766 participants in the Women\u2019s Health Initiative Memory Study in the late 1990s, according to the study\u2019s press release.\u00a0<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/health\/key-fitness-measure-strong-predictor-longevity-after-certain-age-study-finds\" target=\"_blank\" rel=\"noopener\"><strong><u>KEY FITNESS MEASURE IS STRONG PREDICTOR OF LONGEVITY AFTER CERTAIN AGE, STUDY FINDS<\/u><\/strong><\/a><\/p>\n<p>The women ranged from 65 to 79 years of age and showed no signs of <a href=\"https:\/\/www.foxnews.com\/category\/health\/brain-health\" target=\"_blank\" rel=\"noopener\">cognitive decline<\/a> at the start of the study.<\/p>\n<p>After tracking the participants for up to 25 years, the researchers concluded that the biomarker phosphorylated tau 217 (p-tau217) was &#8220;strongly associated&#8221; with future mild cognitive impairment and dementia.\u00a0<\/p>\n<p>Women who had higher levels of p-tau217 at the beginning of the study were &#8220;much more likely&#8221; to develop the disease. The findings were published today in JAMA Network Open.<\/p>\n<p>&#8220;The key takeaway is that our study suggests it may be possible to detect risk of dementia two decades in advance using a simple blood test in <a href=\"https:\/\/www.foxnews.com\/category\/health\/geriatric-health\" target=\"_blank\" rel=\"noopener\">older women<\/a>,&#8221; first author Aladdin H. Shadyab, PhD, UC San Diego associate professor of public health and medicine, told Fox News Digital.\u00a0<\/p>\n<p>&#8220;Our findings show that the blood biomarker p-tau217 could help identify individuals at higher risk for dementia long before symptoms begin,&#8221; he added.<\/p>\n<p>This long lead time could open the door to earlier <a href=\"https:\/\/www.foxnews.com\/category\/health\/healthy-living\" target=\"_blank\" rel=\"noopener\">prevention strategies<\/a> and more targeted monitoring, rather than waiting until memory problems are already affecting daily life, according to Shadyab.<\/p>\n<p>&#8220;As the research advances, these biomarkers may help us identify who is at greatest risk and develop strategies to delay or prevent dementia,&#8221; he said.<\/p>\n<p>This risk relationship wasn\u2019t the same across the board, however. Women over 70 with higher p-tau217 levels had &#8220;poorer cognitive outcomes&#8221; compared to those under 70, as did those with the APOE \u03b54 gene, which is a known risk factor for <a href=\"https:\/\/www.foxnews.com\/category\/health\/nervous-system-health\/alzheimers\" target=\"_blank\" rel=\"noopener\">Alzheimer\u2019s disease<\/a>.<\/p>\n<p>The study also found that p-tau217 was a stronger predictor of dementia in women who were randomly assigned to receive estrogen and progestin hormone therapy compared to those who received a placebo.<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/newsletters?cmpid=fnfirstnl\" target=\"_blank\" rel=\"noopener\"><strong><u>CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER<\/u><\/strong><\/a><\/p>\n<p>&#8220;Blood-based biomarkers like p-tau217 are especially promising because they are far less invasive and potentially more accessible than brain imaging or spinal fluid tests,&#8221; said senior author Linda K. McEvoy, PhD, senior investigator at Kaiser Permanente Washington Health Research Institute and professor emeritus at the Herbert Wertheim School of Public Health, in the release.\u00a0<\/p>\n<p>&#8220;This is important for <a href=\"https:\/\/www.foxnews.com\/category\/health\/medical-research\" target=\"_blank\" rel=\"noopener\">accelerating research<\/a> into the factors that affect the risk of dementia and for evaluating strategies that may reduce risk.&#8221;<\/p>\n<p>Blood tests for Alzheimer&#8217;s disease are still being studied and are not recommended for routine screening in people without symptoms, Shadyab\u00a0noted.\u00a0<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/category\/lifestyle\/quizzes\" target=\"_blank\" rel=\"noopener\"><strong><u>TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ<\/u><\/strong><\/a><\/p>\n<p>More research is needed before this approach can be considered for clinical use prior to cognitive symptoms.\u00a0<\/p>\n<p>Future studies should investigate how other factors \u2014 like genetics, hormone therapy and age-related <a href=\"https:\/\/www.foxnews.com\/health\" target=\"_blank\" rel=\"noopener\">medical conditions<\/a> \u2014 might interact with plasma p-tau217, the researchers added.<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/health\" target=\"_blank\" rel=\"noopener\"><strong><u>CLICK HERE FOR MORE HEALTH STORIES<\/u><\/strong><\/a><\/p>\n<p>&#8220;The study examined only older women, so the findings may not necessarily apply to men or younger populations,&#8221; Shadyab noted. &#8220;We also examined overall dementia outcomes rather than specific subtypes such as Alzheimer\u2019s disease.&#8221;<\/p>\n<\/div>\n<p><a href=\"https:\/\/www.foxnews.com\/health\/lurking-dementia-risk-exposed-breakthrough-test-25-years-before-symptoms\">Source &#8211; https:\/\/www.foxnews.com\/health\/lurking-dementia-risk-exposed-breakthrough-test-25-years-before-symptoms <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new blood test could determine a woman\u2019s dementia risk as early as 25 years before symptoms emerge. That\u2019s according to new research from the [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":{"twitter_2902945987_2902945987":""},"rop_publish_now_history":[],"rop_publish_now_status":"pending","footnotes":""},"categories":[16563],"tags":[],"stock_ticker":[],"class_list":["post-123799","post","type-post","status-publish","format-standard","hentry","category-market-news","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Lurking dementia risk exposed by breakthrough test 25 years before symptoms - Wall Street PR<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cablemanpro.com\/wallstreetpr\/lurking-dementia-risk-exposed-by-breakthrough-test-25-years-before-symptoms-123799\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lurking dementia risk exposed by breakthrough test 25 years before symptoms - Wall Street PR\" \/>\n<meta property=\"og:description\" content=\"A new blood test could determine a woman\u2019s dementia risk as early as 25 years before symptoms emerge. 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