{"id":113239,"date":"2025-12-10T07:00:46","date_gmt":"2025-12-10T12:00:46","guid":{"rendered":"https:\/\/cablemanpro.com\/wallstreetpr\/new-ozempic-alternative-diabetes-pill-burns-fat-without-muscle-loss-study-suggests-113239"},"modified":"2025-12-10T07:00:46","modified_gmt":"2025-12-10T12:00:46","slug":"new-ozempic-alternative-diabetes-pill-burns-fat-without-muscle-loss-study-suggests","status":"publish","type":"post","link":"https:\/\/cablemanpro.com\/wallstreetpr\/new-ozempic-alternative-diabetes-pill-burns-fat-without-muscle-loss-study-suggests-113239","title":{"rendered":"New Ozempic-alternative diabetes pill burns fat without muscle loss, study suggests"},"content":{"rendered":"<div>\n<p>Scientists in Sweden have created a new pill designed to help the body burn fat and <a href=\"https:\/\/www.foxnews.com\/category\/health\/diabetes\/diabetes-type-2\" target=\"_blank\" rel=\"noopener\">control blood sugar<\/a> in a different way than popular GLP-1 drugs, like Ozempic.<\/p>\n<p>While injectable GLP-1s work by suppressing appetite, this new treatment boosts metabolism in the muscles.<\/p>\n<p>A study led by researchers at Karolinska Institutet and Stockholm University included both an early animal study and a human clinical trial with 48 healthy adults and 25 people with type 2 diabetes, according to a press release.<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/health\/new-weight-loss-shot-shows-major-fat-reduction-trial-experts-urge-caution\" target=\"_blank\" rel=\"noopener\"><strong>NEW WEIGHT-LOSS SHOT SHOWS MAJOR FAT REDUCTION, BUT EXPERTS URGE CAUTION<\/strong><\/a><\/p>\n<p>The <a href=\"https:\/\/www.foxnews.com\/health\/weight-loss-could-just-pill-away-study-new-medication-suggests\" target=\"_blank\" rel=\"noopener\">new oral medication<\/a> was found to successfully control blood glucose, boost fat burning and retain muscle mass in animals, while getting high marks for tolerability and safety in humans.<\/p>\n<p>It was also found to have fewer side effects than GLP-1s like semaglutides and tirzepatides, which are known to cause appetite loss, gastrointestinal distress and muscle wasting, the researchers noted.<\/p>\n<p>The <a href=\"https:\/\/www.foxnews.com\/category\/health\/healthy-living\/medications\" target=\"_blank\" rel=\"noopener\">experimental medication<\/a> uses a new form of beta-2 agonist that benefits muscle function while also avoiding overstimulation of the heart, which has been identified as a potential safety concern of older versions.<\/p>\n<p>The findings were published this week in the journal Cell.<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/health\/weight-loss-drugs-now-linked-cancer-protection-women-major-new-study-reveals\" target=\"_blank\" rel=\"noopener\"><strong>WEIGHT-LOSS DRUGS NOW LINKED TO CANCER PROTECTION IN WOMEN, MAJOR NEW STUDY REVEALS<\/strong><\/a><\/p>\n<p>Because the new oral drug acts via a different mechanism than appetite-suppressing medications, it could be used alone or in combination with GLP-1s, the researchers noted.<\/p>\n<p>&#8220;Our results point to a future where we can improve metabolic health without losing muscle mass,&#8221; said Tore Bengtsson, professor at the Department of Molecular Bioscience at Wenner-Gren Institute, Stockholm University, in the release. &#8220;Muscles are important in both type 2 diabetes <a href=\"https:\/\/www.foxnews.com\/category\/health\/nutrition-and-fitness\/obesity\" target=\"_blank\" rel=\"noopener\">and obesity<\/a>, and muscle mass is also directly correlated with life expectancy.&#8221;<\/p>\n<p>This medication has the potential to be of &#8220;great importance&#8221; for patients with <a href=\"https:\/\/www.foxnews.com\/category\/health\/diabetes\" target=\"_blank\" rel=\"noopener\">type 2 diabetes<\/a> and obesity, according to Shane C. Wright, assistant professor at the Department of Physiology and Pharmacology at Karolinska Institutet.<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/newsletters?cmpid=fnfirstnl\" target=\"_blank\" rel=\"noopener\"><strong>CLICK HERE TO SIGN UP FOR OUR HEALTH NEWSLETTER<\/strong><\/a><\/p>\n<p>&#8220;Our substance appears to promote <a href=\"https:\/\/www.foxnews.com\/category\/health\/nutrition-and-fitness\/weight-loss\" target=\"_blank\" rel=\"noopener\">healthy weight loss<\/a> and, in addition, patients do not have to take injections,&#8221; he added.<\/p>\n<p>Dr. Trey Wickham, interim chief of the Division of Endocrinology, Diabetes &amp; Metabolism at VCU Health in Richmond, Virginia, was not involved in the study but shared his reaction to the publication in the journal Cell.<\/p>\n<p>&#8220;This compound\u2019s mechanism of action could address some specific metabolic concerns with previous weight reduction therapies, such as the loss of both muscle and fat tissue,&#8221; Wickham told Fox News Digital.\u00a0\u00a0<\/p>\n<p>&#8220;Although the reported preliminary results are interesting, rigorous testing involving larger longitudinal trials are necessary to ensure human <a href=\"https:\/\/www.foxnews.com\/health\" target=\"_blank\" rel=\"noopener\">long-term safety<\/a> and understand the potential role of this compound in the comprehensive, evidence-based treatment of obesity and diabetes.&#8221;<\/p>\n<p>The study had some limitations, the researchers noted, chiefly that the <a href=\"https:\/\/www.foxnews.com\/category\/health\/medical-research\" target=\"_blank\" rel=\"noopener\">preclinical studies<\/a> in mice fail to capture the &#8220;complex nature of these diseases&#8221; in humans.<\/p>\n<p>Structural studies are needed to understand exactly how the drug works.<\/p>\n<p>&#8220;Our phase 1 data show that compound 15 is well-tolerated; however, conclusive clinical efficacy data (on how the drug controls glucose metabolism) are currently still lacking.&#8221;<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/health\" target=\"_blank\" rel=\"noopener\"><strong>CLICK HERE FOR MORE HEALTH STORIES<\/strong><\/a><\/p>\n<p>Looking ahead, the company that developed the drug, Atrogi AB, plans to conduct a larger phase 2 <a href=\"https:\/\/www.foxnews.com\/category\/health\/medical-research\" target=\"_blank\" rel=\"noopener\">clinical trial<\/a> with a larger, more diverse population, including people with obesity.<\/p>\n<p><a href=\"https:\/\/www.foxnews.com\/category\/lifestyle\/quizzes\" target=\"_blank\" rel=\"noopener\"><strong>TEST YOURSELF WITH OUR LATEST LIFESTYLE QUIZ<\/strong><\/a><\/p>\n<p>The study was supported in part by the Swedish Research Council, the Swedish Society for Medical Research and the Novo Nordisk Foundation.<\/p>\n<p>Uppsala University, University of Copenhagen, Monash University and University of Queensland all collaborated with the lead researchers.<\/p>\n<\/div>\n<p><a href=\"https:\/\/www.foxnews.com\/health\/new-ozempic-alternative-diabetes-pill-burns-fat-without-muscle-loss-study-suggests\">Source &#8211; https:\/\/www.foxnews.com\/health\/new-ozempic-alternative-diabetes-pill-burns-fat-without-muscle-loss-study-suggests <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Scientists in Sweden have created a new pill designed to help the body burn fat and control blood sugar in a different way than popular [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"rop_custom_images_group":[],"rop_custom_messages_group":[],"rop_publish_now":"initial","rop_publish_now_accounts":{"twitter_2902945987_2902945987":""},"rop_publish_now_history":[],"rop_publish_now_status":"pending","footnotes":""},"categories":[16563],"tags":[],"stock_ticker":[],"class_list":["post-113239","post","type-post","status-publish","format-standard","hentry","category-market-news","entry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - 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